Molecular phylogeny and missense mutations at envelope proteins across coronaviruses

Authors

Sk Sarif Hassan
Pabitra Pal Choudhury, Indian Statistical Institute, Kolkata
Bidyut Roy, Indian Statistical Institute, Kolkata

Article Type

Research Article

Publication Title

Genomics

Abstract

Envelope (E) protein is one of the structural viroporins (76–109 amino acids long) present in the coronavirus. Sixteen sequentially different E-proteins were observed from a total of 4917 available complete SARS-CoV-2 genomes as on 18th June 2020 in the NCBI database. The missense mutations over the envelope protein across various coronaviruses of the β-genus were analyzed to know the immediate parental origin of the envelope protein of SARS-CoV-2. The evolutionary origin is also endorsed by the phylogenetic analysis of the envelope proteins comparing sequence homology as well as amino acid conservations.

First Page

4993

Last Page

5004

DOI

10.1016/j.ygeno.2020.09.014

Publication Date

11-1-2020

Comments

Open Access, Bronze, Green

Recommended Citation

Hassan, Sk Sarif; Choudhury, Pabitra Pal; and Roy, Bidyut, "Molecular phylogeny and missense mutations at envelope proteins across coronaviruses" (2020). Journal Articles. 76.
https://digitalcommons.isical.ac.in/journal-articles/76