MODELING BURULI ULCER TRANSMISSION: SEIR-SEI ANALYSIS WITH IMMUNITY LOSS AND ARSENIC CONTAMINATION

Article Type

Research Article

Publication Title

South East Asian Journal of Mathematics and Mathematical Sciences

Abstract

This article presents a novel mathematical model to explore the transmission dynamics of Mycobacterium ulcerans (MU) infection, focusing on the water-borne spread. Using SEIR and SEI models for human and water-bug populations, it considers factors such as disease-related deaths and arsenic-contaminated water. The analysis determines the basic reproduction number (R0 ), which dictates the stability of disease-free and endemic equilibria. The study underscores the importance of controlling Buruli ulcer transmission, offering valuable insights for global health management.

First Page

165

Last Page

190

DOI

10.56827/SEAJMMS.2025.2101.14

Publication Date

1-1-2025

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