Synchronization and metabolic energy consumption in stochastic Hodgkin-Huxley neurons: Patch size and drug blockers
Article Type
Research Article
Publication Title
Neurocomputing
Abstract
In this work, a stochastic Langevin approach is adopted to coupled Hodgkin-Huxley neuron system to elucidate the role of channel noise in the kinetics and energetics of spiking of action potential and the synchronization between neurons. The size of patch plays a pivotal role in synchronization and metabolic energy consumption. The behavior of postsynaptic neuron is explored by taking three different patch size ranges from noise enhanced phase to dead range state before reaching a deterministic limit. We also discuss the effect of sodium and potassium channel blockers on kinetic and energetic characteristics of synchronization and metabolic energy consumption rate.
First Page
222
Last Page
234
DOI
10.1016/j.neucom.2020.10.006
Publication Date
1-21-2021
Recommended Citation
Pal, Krishnendu; Ghosh, Dibakar; and Gangopadhyay, Gautam, "Synchronization and metabolic energy consumption in stochastic Hodgkin-Huxley neurons: Patch size and drug blockers" (2021). Journal Articles. 2120.
https://digitalcommons.isical.ac.in/journal-articles/2120