Fractal and mathematical morphology in intricate comparison between tertiary protein structures

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Research Article

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Computer Methods in Biomechanics and Biomedical Engineering: Imaging and Visualization


Intricate comparison between two given tertiary structures of proteins is as important as the comparison of their functions. In literature, several algorithms have been devised to compute the similarity and dissimilarity among protein structures. But, these algorithms compare protein structures by structural alignment of the protein backbones which are usually unable to determine precise differences. In this paper, an attempt has been made to compute the similarities and dissimilarities among tertiary protein structures using the fundamental mathematical morphology operations and fractal geometry which can decipher the intricate differences. In doing so, two techniques have been used here in determining the global as well as local similarity in atomic level of the protein molecules. This intricate structural difference would provide an insight to biologists to understand the protein structures and their functions in more precise fashion.

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All Open Access, Green

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