Fractal and mathematical morphology in intricate comparison between tertiary protein structures

Article Type

Research Article

Publication Title

Computer Methods in Biomechanics and Biomedical Engineering: Imaging and Visualization

Abstract

Intricate comparison between two given tertiary structures of proteins is as important as the comparison of their functions. In literature, several algorithms have been devised to compute the similarity and dissimilarity among protein structures. But, these algorithms compare protein structures by structural alignment of the protein backbones which are usually unable to determine precise differences. In this paper, an attempt has been made to compute the similarities and dissimilarities among tertiary protein structures using the fundamental mathematical morphology operations and fractal geometry which can decipher the intricate differences. In doing so, two techniques have been used here in determining the global as well as local similarity in atomic level of the protein molecules. This intricate structural difference would provide an insight to biologists to understand the protein structures and their functions in more precise fashion.

First Page

192

Last Page

203

DOI

10.1080/21681163.2016.1214850

Publication Date

3-4-2018

Comments

All Open Access, Green

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