Cochran–Mantel–Haenszel test with bivariate binomial model on surrogate marker analysis

Article Type

Research Article

Publication Title

Communications in Statistics Case Studies Data Analysis and Applications

Abstract

The standard Cochran–Mantel–Haenszel (CMH) test is useful for testing common odds ratio for multiple 2 × 2 contingency tables under the assumption of hypergeometric/product-binomial model. In this article, we shed light on the modification of the CMH test in a bivariate binomial setup with the presence of surrogate markers. We illustrate that the surrogate information can be successfully incorporated to improve the performance of the CMH test procedure by using a bivariate binomial model.

First Page

142

Last Page

150

DOI

10.1080/23737484.2018.1536862

Publication Date

10-2-2018

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