A response adaptive design for ordinal categorical responses weighing the cumulative odds ratios

Authors

Atanu Biswas, Indian Statistical Institute, Kolkata
Rahul Bhattacharya, University of Calcutta
Soumyadeep Das, Bidhannagar Government College

Article Type

Research Article

Publication Title

Biostatistics and Epidemiology

Abstract

Weighing the cumulative odds ratios suitably, a two treatment response adaptive design for phase III clinical trial is proposed for ordinal categorical responses. Properties of the proposed design are investigated theoretically as well as empirically. Applicability of the design is further verified using a data pertaining to a real clinical trial with trauma patients, where the responses are observed in an ordinal categorical scale.

First Page

109

Last Page

125

DOI

10.1080/24709360.2019.1660111

Publication Date

1-1-2019

Recommended Citation

Biswas, Atanu; Bhattacharya, Rahul; and Das, Soumyadeep, "A response adaptive design for ordinal categorical responses weighing the cumulative odds ratios" (2019). Journal Articles. 1028.
https://digitalcommons.isical.ac.in/journal-articles/1028