Analysis of Gene Expression Data in a Dependent Set-up

Document Type

Book Chapter

Publication Title

Indian Statistical Institute Series

Abstract

Gene expression data provides us with a big picture of the activity of the genes under study. However, it is of great interest to see whether the same gene behaves in the same way in tumour tissue as well as normal tissue. Or two genes in the same or different pathways behave similarly. Especially in studying cancer, it is expected that at least for some genes, expression patterns vary in different types of tissues or cells from different regions. In other words, a few genes might not show any significant differential signature in different tissues, while others might. One gene might act in synergy with another gene and show some significant activity or change in expression level. Naturally, this demands a thorough understanding and detailed study to get a clear picture of the gene expression pattern.

First Page

99

Last Page

128

DOI

10.1007/978-981-99-3220-7_5

Publication Date

1-1-2023

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