Bounds on generalized family-wise error rates for normal distributions

Article Type

Research Article

Publication Title

Statistical Papers

Abstract

The Bonferroni procedure has been one of the foremost frequentist approaches for controlling the family-wise error rate (FWER) in simultaneous inference. However, many scientific disciplines often require less stringent error rates. One such measure is the generalized family-wise error rate (gFWER) proposed (Lehmann and Romano in Ann Stat 33(3):1138–1154, 2005, https://doi.org/10.1214/009053605000000084). FWER or gFWER controlling methods are considered highly conservative in problems with a moderately large number of hypotheses. Although, the existing literature lacks a theory on the extent of the conservativeness of gFWER controlling procedures under dependent frameworks. In this note, we address this gap in a unified manner by establishing upper bounds for the gFWER under arbitrarily correlated multivariate normal setups with moderate dimensions. Towards this, we derive a new probability inequality which, in turn, extends and sharpens a classical inequality. Our results also generalize a recent related work by the first author.

First Page

2313

Last Page

2326

DOI

10.1007/s00362-023-01487-0

Publication Date

6-1-2024

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