Title

Global analysis and optimal control of a periodic visceral leishmaniasis model

Article Type

Research Article

Publication Title

Mathematics

Abstract

In this paper, we propose and analyze a mathematical model for the dynamics of visceral leishmaniasis with seasonality. Our results show that the disease-free equilibrium is globally asymptotically stable under certain conditions when R0, the basic reproduction number, is less than unity. When R0 > 1 and under some conditions, then our system has a unique positive ω-periodic solution that is globally asymptotically stable. Applying two controls, vaccination and treatment, to our model forces the system to be non-periodic, and all fractions of infected populations settle on a very low level.

DOI

10.3390/math5040080

Publication Date

12-14-2017

Comments

Open Access, Gold, Green

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